CRBN ligand-422 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be effectively conjugated to target protein ligands through a linker to create PROTACs, enabling targeted protein degradation. CRBN ligand-422 is valuable in research applications focused on proteolysis-targeting chimeras and the modulation of specific protein levels within cellular pathways.
CRBN ligand-422 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be effectively conjugated to target protein ligands through a linker to create PROTACs, enabling targeted protein degradation. CRBN ligand-422 is valuable in research applications focused on proteolysis-targeting chimeras and the modulation of specific protein levels within cellular pathways.
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