Documents & Downloads

CRBN ligand-430

Ligand for E3 Ligase

CRBN ligand-430 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound is designed for use in PROTAC (proteolysis targeting chimera) technology, allowing for targeted degradation of specific proteins when linked to a target protein ligand through a suitable linker. Its application is pivotal in the study of protein homeostasis and therapeutic development in diseases where protein dysregulation is a factor.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925071-04-9
Applications	Ligand for E3 Ligase
Formula	C₁₄H₁₃N₃O₄
Molecular Weight	287.28
SMILES	O=C(O)C=1C=CC=2C(=NN(C2C1)C)C3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.