CRBN ligand-435 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound serves as a key component in the development of PROTACs (proteolysis-targeting chimeras), allowing for targeted degradation of specific proteins in cellular assays. Its utility spans various research applications, including drug discovery and the study of protein homeostasis and degradation pathways.
CRBN ligand-435 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound serves as a key component in the development of PROTACs (proteolysis-targeting chimeras), allowing for targeted degradation of specific proteins in cellular assays. Its utility spans various research applications, including drug discovery and the study of protein homeostasis and degradation pathways.
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