CRBN ligand-436 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be utilized in the development of PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand through a suitable linker. Its application includes targeted protein degradation studies, providing an innovative approach for modulating protein levels in various biological contexts.
CRBN ligand-436 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be utilized in the development of PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand through a suitable linker. Its application includes targeted protein degradation studies, providing an innovative approach for modulating protein levels in various biological contexts.
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