Documents & Downloads

CRBN ligand-444

Ligand for E3 Ligase

CRBN ligand-444 acts as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. It is designed for use in PROTAC (proteolysis-targeting chimeras) applications by enabling the linkage of a target protein ligand through a suitable linker. This compound is essential for studies involving targeted protein degradation and modulation of cellular processes associated with protein turnover.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925102-40-3
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₀N₄O₃
Molecular Weight	270.25
SMILES	O=CC1=CC(=CC=2C=NC=NC12)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.