CRBN ligand-447 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this protein for targeted protein degradation. It can be conjugated to a target protein ligand through a linker to create a PROTAC (proteolysis-targeting chimera), enabling selective degradation of specific proteins in cellular assays. This compound is valuable for research in targeted therapies and protein homeostasis studies.
CRBN ligand-447 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this protein for targeted protein degradation. It can be conjugated to a target protein ligand through a linker to create a PROTAC (proteolysis-targeting chimera), enabling selective degradation of specific proteins in cellular assays. This compound is valuable for research in targeted therapies and protein homeostasis studies.
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