CRBN ligand-450 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), designed to facilitate the recruitment of CRBN to target proteins. This compound can be effectively conjugated to a target protein ligand through a linker to generate a proteolysis-targeting chimera (PROTAC). Its application in targeted protein degradation research provides an innovative approach to modulating protein levels and studying cellular processes.
CRBN ligand-450 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), designed to facilitate the recruitment of CRBN to target proteins. This compound can be effectively conjugated to a target protein ligand through a linker to generate a proteolysis-targeting chimera (PROTAC). Its application in targeted protein degradation research provides an innovative approach to modulating protein levels and studying cellular processes.
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