CRBN ligand-453 is an E3 ubiquitin ligase ligand that specifically targets cereblon (CRBN) to facilitate its recruitment. This compound is designed to be conjugated to a target protein ligand through a linker, enabling the formation of a PROTAC (Proteolysis Targeting Chimera). It provides a powerful tool for targeted protein degradation studies and is applicable in research aimed at modulating protein levels in various biological contexts.
CRBN ligand-453 is an E3 ubiquitin ligase ligand that specifically targets cereblon (CRBN) to facilitate its recruitment. This compound is designed to be conjugated to a target protein ligand through a linker, enabling the formation of a PROTAC (Proteolysis Targeting Chimera). It provides a powerful tool for targeted protein degradation studies and is applicable in research aimed at modulating protein levels in various biological contexts.
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