CRBN ligand-484 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be conjugated to target protein ligands through a linker, enabling the development of PROTACs that promote targeted protein degradation. Its utility in research includes exploring the mechanisms of ubiquitin-proteasome system modulation and protein homeostasis in cellular contexts.
CRBN ligand-484 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be conjugated to target protein ligands through a linker, enabling the development of PROTACs that promote targeted protein degradation. Its utility in research includes exploring the mechanisms of ubiquitin-proteasome system modulation and protein homeostasis in cellular contexts.
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