CRBN ligand-485 is an E3 ubiquitin ligase cereblon (CRBN) ligand that facilitates the recruitment of the cereblon protein. This compound is utilized in the development of PROTACs (Proteolysis Targeting Chimeras) by linking to target protein ligands through a linker. Its primary application lies in targeted protein degradation research, enabling the modulation of specific protein levels in cellular systems for therapeutic investigations.
CRBN ligand-485 is an E3 ubiquitin ligase cereblon (CRBN) ligand that facilitates the recruitment of the cereblon protein. This compound is utilized in the development of PROTACs (Proteolysis Targeting Chimeras) by linking to target protein ligands through a linker. Its primary application lies in targeted protein degradation research, enabling the modulation of specific protein levels in cellular systems for therapeutic investigations.
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