CRBN ligand-485

Catalog No.: A81246
Ligand for E3 Ligase
CRBN ligand-485 is an E3 ubiquitin ligase cereblon (CRBN) ligand that facilitates the recruitment of the cereblon protein. This compound is utilized in the development of PROTACs (Proteolysis Targeting Chimeras) by linking to target protein ligands through a linker. Its primary application lies in targeted protein degradation research, enabling the modulation of specific protein levels in cellular systems for therapeutic investigations.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-485 is an E3 ubiquitin ligase cereblon (CRBN) ligand that facilitates the recruitment of the cereblon protein. This compound is utilized in the development of PROTACs (Proteolysis Targeting Chimeras) by linking to target protein ligands through a linker. Its primary application lies in targeted protein degradation research, enabling the modulation of specific protein levels in cellular systems for therapeutic investigations.
Product Information
Catalog NumA81246
FormulaC13H14N4O2
Molecular Weight258.28
CAS Number2925097-49-8
SMILESO=C1NC(=O)CCN1C=2C=C(N)C=C3C2C=CN3C
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