CRBN ligand-488 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN for targeted protein degradation. This compound can be conjugated with a target protein ligand through a linker to create a proteolysis-targeting chimera (PROTAC). Its utility in targeted protein elimination makes it an important tool for investigating cellular processes and therapeutic applications in cancer and other diseases.
CRBN ligand-488 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN for targeted protein degradation. This compound can be conjugated with a target protein ligand through a linker to create a proteolysis-targeting chimera (PROTAC). Its utility in targeted protein elimination makes it an important tool for investigating cellular processes and therapeutic applications in cancer and other diseases.
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