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CRBN ligand-495

Ligand for E3 Ligase

CRBN ligand-495 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of cereblon to specific target proteins. This compound can be utilized in the construction of PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand via an appropriate linker. The application of CRBN ligand-495 offers significant potential in targeted protein degradation studies and therapeutic development within cellular and molecular biology research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925093-30-5
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₄N₄O₂
Molecular Weight	258.28
SMILES	O=C1NC(=O)CCN1C=2C=C(N)C3=C(C=CN3C)C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.