CRBN ligand-497 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be coupled with a ligand for a target protein through a linker, enabling the formation of a PROTAC (proteolysis-targeting chimera). CRBN ligand-497 is utilized in research to explore targeted protein degradation pathways and to study the role of the ubiquitin-proteasome system in cellular regulation.
CRBN ligand-497 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be coupled with a ligand for a target protein through a linker, enabling the formation of a PROTAC (proteolysis-targeting chimera). CRBN ligand-497 is utilized in research to explore targeted protein degradation pathways and to study the role of the ubiquitin-proteasome system in cellular regulation.
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