CRBN ligand-507

Catalog No.: A80818
Ligand for E3 Ligase
CRBN ligand-507 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of the cereblon protein, making it a valuable tool in targeted protein degradation research. CRBN ligand-507 can be conjugated to a target-specific ligand through a linker, enabling the creation of PROTACs for the selective degradation of intracellular proteins. Its applications include studying protein turnover and modulation of cellular pathways.
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Biological Activity
DescriptionCRBN ligand-507 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of the cereblon protein, making it a valuable tool in targeted protein degradation research. CRBN ligand-507 can be conjugated to a target-specific ligand through a linker, enabling the creation of PROTACs for the selective degradation of intracellular proteins. Its applications include studying protein turnover and modulation of cellular pathways.
Product Information
Catalog NumA80818
FormulaC14H11N3O3
Molecular Weight269.26
CAS Number2925088-55-5
SMILESO=CC1=CC=C(C=2C=CN=CC12)N3C(=O)NC(=O)CC3
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