CRBN ligand-511 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the targeted recruitment of CRBN. This compound can be conjugated to target protein ligands through a linker to create proteolysis-targeting chimeras (PROTACs). Its application in degrading specific proteins makes it a valuable tool in chemical biology and therapeutic development for modulating cellular pathways.
CRBN ligand-511 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the targeted recruitment of CRBN. This compound can be conjugated to target protein ligands through a linker to create proteolysis-targeting chimeras (PROTACs). Its application in degrading specific proteins makes it a valuable tool in chemical biology and therapeutic development for modulating cellular pathways.
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