CRBN ligand-526

Catalog No.: A80939
Ligand for E3 Ligase
CRBN ligand-526 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be employed in the development of PROTACs (proteolysis targeting chimeras) by linking it to a target protein ligand through a suitable linker. Research applications include targeted protein degradation studies, enabling the exploration of novel therapeutic strategies in various disease models.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-526 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be employed in the development of PROTACs (proteolysis targeting chimeras) by linking it to a target protein ligand through a suitable linker. Research applications include targeted protein degradation studies, enabling the exploration of novel therapeutic strategies in various disease models.
Product Information
Catalog NumA80939
FormulaC12H10N4O3
Molecular Weight258.24
CAS Number2925074-71-9
SMILESO=CC=1C=C2NN=CC2=C(C1)N3C(=O)NC(=O)CC3
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