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CRBN ligand-527

Ligand for E3 Ligase

CRBN ligand-527 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN). It effectively recruits the CRBN protein and can be utilized to create a PROTAC by linking it to a target protein ligand through a suitable linker. This compound is valuable for research applications focused on targeted protein degradation and the study of protein turnover mechanisms.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925073-94-3
Applications	Ligand for E3 Ligase
Formula	C₁₄H₁₁N₃O₄
Molecular Weight	285.26
SMILES	O=C(O)C1=CC=C(C2=NC=CC=C21)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.