CRBN ligand-527

Catalog No.: A81219
Ligand for E3 Ligase
CRBN ligand-527 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN). It effectively recruits the CRBN protein and can be utilized to create a PROTAC by linking it to a target protein ligand through a suitable linker. This compound is valuable for research applications focused on targeted protein degradation and the study of protein turnover mechanisms.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-527 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN). It effectively recruits the CRBN protein and can be utilized to create a PROTAC by linking it to a target protein ligand through a suitable linker. This compound is valuable for research applications focused on targeted protein degradation and the study of protein turnover mechanisms.
Product Information
Catalog NumA81219
FormulaC14H11N3O4
Molecular Weight285.26
CAS Number2925073-94-3
SMILESO=C(O)C1=CC=C(C2=NC=CC=C21)N3C(=O)NC(=O)CC3
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