CRBN ligand-528

Catalog No.: A81061
Ligand for E3 Ligase
CRBN ligand-528 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN). It serves as a molecular tool to recruit the CRBN protein, facilitating targeted protein degradation when conjugated to a target protein ligand through a suitable linker. This compound is essential for research applications focused on understanding ubiquitin-mediated proteolysis and developing PROTAC (Proteolysis Targeting Chimera) strategies for therapeutic intervention.
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Biological Activity
DescriptionCRBN ligand-528 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN). It serves as a molecular tool to recruit the CRBN protein, facilitating targeted protein degradation when conjugated to a target protein ligand through a suitable linker. This compound is essential for research applications focused on understanding ubiquitin-mediated proteolysis and developing PROTAC (Proteolysis Targeting Chimera) strategies for therapeutic intervention.
Product Information
Catalog NumA81061
FormulaC14H11N3O4
Molecular Weight285.26
CAS Number2925073-57-8
SMILESO=C(O)C=1N=C2C=CC(=CC2=CC1)N3C(=O)NC(=O)CC3
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