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CRBN ligand-531

Ligand for E3 Ligase

CRBN ligand-531 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this protein for targeted protein degradation. This compound can be utilized in the development of PROTACs (proteolysis-targeting chimeras) by connecting it to a target protein ligand through a suitable linker. Its application in drug discovery and development makes it a valuable tool for studying protein regulation and degradation pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3030284-26-2
Applications	Ligand for E3 Ligase
Formula	C₁₇H₁₉ClN₂O₃
Molecular Weight	334.80
SMILES	O=CC1CCN(C2=CC=C(C(Cl)=C2)C3C(=O)NC(=O)CC3)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.