Documents & Downloads

CRBN ligand-553

Ligand for E3 Ligase

CRBN ligand-553 is a specific ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. It can be utilized to conjugate with target protein ligands via a linker to create Proteolysis Targeting Chimeras (PROTACs). This compound is crucial for studying targeted protein degradation and has applications in drug development and cellular biology research.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925100-20-3
Applications	Ligand for E3 Ligase
Formula	C₁₂H₁₁BrN₄O₂
Molecular Weight	323.15
SMILES	O=C1NC(=O)CCN1C=2C=C(Br)C3=C(C=NN3C)C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.