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CRBN ligand-563

Ligand for E3 Ligase

CRBN ligand-563 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be utilized in the design of PROTACs (proteolysis-targeting chimeras) by linking it with target protein ligands via a suitable linker. Its applications include targeted protein degradation studies and exploring novel therapeutic strategies in various diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925095-87-8
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₅N₅O₂
Molecular Weight	273.30
SMILES	O=C1NC(=O)CCN1C=2C=CC3=C(C=NN3CCN)C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.