Fig. 1 · Structure

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CRBN ligand-568

Ligand for E3 Ligase

CRBN ligand-568 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound can be equipped with a linker to create a PROTAC (proteolysis-targeting chimeras), enabling targeted protein degradation. CRBN ligand-568 is beneficial for studying protein regulation and ubiquitination processes in various biological contexts.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2925092-62-0
Applications Ligand for E3 Ligase
Formula C14H13N3O4
Molecular Weight 287.28
SMILES
O=C(O)CN1C=CC=2C=C(C=CC21)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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