CRBN ligand-577

Catalog No.: A81220
Ligand for E3 Ligase
CRBN ligand-577 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this protein in targeted protein degradation applications. This compound can be conjugated to a target protein ligand through a suitable linker, enabling the formation of a PROTAC (proteolysis-targeting chimera). CRBN ligand-577 supports research in the development of targeted therapies by promoting selective ubiquitination and degradation of specific proteins within the cellular environment.
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5mg
10mg
50mg
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-577 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this protein in targeted protein degradation applications. This compound can be conjugated to a target protein ligand through a suitable linker, enabling the formation of a PROTAC (proteolysis-targeting chimera). CRBN ligand-577 supports research in the development of targeted therapies by promoting selective ubiquitination and degradation of specific proteins within the cellular environment.
Product Information
Catalog NumA81220
FormulaC12H13N5O2
Molecular Weight259.27
CAS Number2925087-91-6
SMILESO=C1NC(=O)CCN1C2=CC=C(N)C=3C=NN(C32)C
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