CRBN ligand-583

Catalog No.: A80934
Ligand for E3 Ligase
CRBN ligand-583 is a small molecule ligand that targets the E3 ubiquitin ligase cereblon (CRBN). It is designed to facilitate the recruitment of CRBN to specific target proteins. By being conjugated to a target protein ligand through a linker, CRBN ligand-583 can be utilized in the development of PROTACs (Proteolysis-targeting chimeras) for targeted protein degradation studies and therapeutic applications in cancer and other diseases.
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Biological Activity
DescriptionCRBN ligand-583 is a small molecule ligand that targets the E3 ubiquitin ligase cereblon (CRBN). It is designed to facilitate the recruitment of CRBN to specific target proteins. By being conjugated to a target protein ligand through a linker, CRBN ligand-583 can be utilized in the development of PROTACs (Proteolysis-targeting chimeras) for targeted protein degradation studies and therapeutic applications in cancer and other diseases.
Product Information
Catalog NumA80934
FormulaC12H11BrN4O2
Molecular Weight323.15
CAS Number2925085-77-2
SMILESO=C1NC(=O)CCN1C2=CC(Br)=CC3=NN(C=C32)C
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