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CRBN ligand-585

Ligand for E3 Ligase

CRBN ligand-585 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. This compound can be conjugated to a target protein ligand through a linker, enabling the formation of PROTACs (proteolysis-targeting chimeras). CRBN ligand-585 is valuable for studies involving targeted protein degradation and elucidating the role of E3 ligases in cellular processes.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925085-13-6
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₀N₄O₄
Molecular Weight	286.25
SMILES	O=C(O)C=1C=C(C=C2N=CN=CC21)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.