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CRBN ligand-587

Ligand for E3 Ligase

CRBN ligand-587 is a ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of CRBN to target proteins, allowing for the targeted degradation of these proteins through the PROTAC (Proteolysis Targeting Chimeras) pathway. CRBN ligand-587 is instrumental in research applications focusing on protein modulation and targeted protein degradation strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925082-48-8
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₀N₄O₄
Molecular Weight	286.25
SMILES	O=C(O)C1=NN=CC=2C=CC(=CC21)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.