Documents & Downloads

CRBN ligand-601

Ligand for E3 Ligase

CRBN ligand-601 is an E3 ubiquitin ligase cereblon (CRBN) ligand that functions by selectively recruiting the cereblon protein. This compound can be effectively conjugated to a target protein ligand through a linker to create a proteolysis-targeting chimera (PROTAC). It serves as a valuable tool for research applications involving targeted protein degradation, providing insights into protein regulation and potential therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925073-23-8
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₅N₅O₂
Molecular Weight	273.30
SMILES	O=C1NC(=O)CCN1C=2C=CC3=NN(C=C3C2)CCN

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.