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CRBN ligand-602

Ligand for E3 Ligase

CRBN ligand-602 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this protein to target substrates. This compound can be utilized in the development of PROTACs (proteolysis-targeting chimeras) by linking it to a target protein ligand through a suitable linker. Its utility in targeted protein degradation makes it a valuable tool for researchers interested in modulating protein levels in cellular systems.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925073-20-5
Applications	Ligand for E3 Ligase
Formula	C₁₂H₁₃N₅O₂
Molecular Weight	259.27
SMILES	O=C1NC(=O)CCN1C=2C=CC3=C(C2)C(=NN3C)N

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.