CRBN ligand-606

Catalog No.: A80761
Ligand for E3 Ligase
CRBN ligand-606 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of the CRBN protein, enabling targeted protein degradation through the formation of PROTACs when linked to specific target protein ligands. It is particularly useful in the study of protein homeostasis and degradation pathways, making it valuable for various research applications in cellular biology and therapeutic development.
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Biological Activity
DescriptionCRBN ligand-606 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of the CRBN protein, enabling targeted protein degradation through the formation of PROTACs when linked to specific target protein ligands. It is particularly useful in the study of protein homeostasis and degradation pathways, making it valuable for various research applications in cellular biology and therapeutic development.
Product Information
Catalog NumA80761
FormulaC13H10N4O4
Molecular Weight286.25
CAS Number2925072-63-3
SMILESO=C(O)C1=NN=CC=2C1=CC=CC2N3C(=O)NC(=O)CC3
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