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CRBN ligand-611

Ligand for E3 Ligase

CRBN ligand-611 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of this essential protein. It is designed to be conjugated to target protein ligands through a linker, enabling the formation of proteolysis-targeting chimeras (PROTACs). This compound is valuable for studies focused on targeted protein degradation and E3 ligase-mediated pathways in cellular biology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2766179-60-4
Applications	Ligand for E3 Ligase
Formula	C₁₆H₁₉N₅O₂
Molecular Weight	313.36
SMILES	O=C1NC(=O)CCN1C2=CC=C(C=3NC=CC23)N4CCNCC4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.