CRBN ligand-615

Catalog No.: A80792
Ligand for E3 Ligase
CRBN ligand-615 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), utilized to recruit the CRBN protein in targeted protein degradation applications. It can be integrated with a target protein ligand through a linker, facilitating the formation of a PROTAC (proteolysis-targeting chimera). This compound enables selective degradation of specific proteins, making it valuable for research in areas such as cancer biology and targeted therapeutics.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-615 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), utilized to recruit the CRBN protein in targeted protein degradation applications. It can be integrated with a target protein ligand through a linker, facilitating the formation of a PROTAC (proteolysis-targeting chimera). This compound enables selective degradation of specific proteins, making it valuable for research in areas such as cancer biology and targeted therapeutics.
Product Information
Catalog NumA80792
FormulaC17H19FN2O3
Molecular Weight318.35
CAS Number2858741-83-8
SMILESO=CC1CCN(C2=CC=C(C=C2F)C3C(=O)NC(=O)CC3)CC1
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