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CRBN ligand-615

Ligand for E3 Ligase

CRBN ligand-615 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), utilized to recruit the CRBN protein in targeted protein degradation applications. It can be integrated with a target protein ligand through a linker, facilitating the formation of a PROTAC (proteolysis-targeting chimera). This compound enables selective degradation of specific proteins, making it valuable for research in areas such as cancer biology and targeted therapeutics.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2858741-83-8
Applications	Ligand for E3 Ligase
Formula	C₁₇H₁₉FN₂O₃
Molecular Weight	318.35
SMILES	O=CC1CCN(C2=CC=C(C=C2F)C3C(=O)NC(=O)CC3)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.