CRBN ligand-616 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This reagent can be conjugated with a target protein ligand through a linker to generate a proteolysis-targeting chimeric molecule (PROTAC). It supports research in targeted protein degradation, offering potential applications in therapeutic development and cellular signaling studies.
CRBN ligand-616 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This reagent can be conjugated with a target protein ligand through a linker to generate a proteolysis-targeting chimeric molecule (PROTAC). It supports research in targeted protein degradation, offering potential applications in therapeutic development and cellular signaling studies.
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