CRBN ligand-617

Catalog No.: A80542
Ligand for E3 Ligase
CRBN ligand-617 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), designed to facilitate the recruitment of CRBN to target proteins. This compound can be conjugated to a ligand that binds to a specific target protein through a linker, enabling the formation of a proteolysis-targeting chimera (PROTAC). CRBN ligand-617 is applicable in studies focused on targeted protein degradation and has significant potential in drug discovery and therapeutic development.
Grouped product items
Size Price Stock Qty
5mg
$80.00
In stock
10mg
$130.00
In stock
25mg
$260.00
In stock
50mg
$410.00
In stock
100mg
$635.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCRBN ligand-617 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), designed to facilitate the recruitment of CRBN to target proteins. This compound can be conjugated to a ligand that binds to a specific target protein through a linker, enabling the formation of a proteolysis-targeting chimera (PROTAC). CRBN ligand-617 is applicable in studies focused on targeted protein degradation and has significant potential in drug discovery and therapeutic development.
Product Information
Catalog NumA80542
FormulaC11H9BrN4O2
Molecular Weight309.12
CAS Number2713620-89-2
SMILESO=C1NC(=O)CCN1C2=CN=C3C(Br)=CC=CN32
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