CRBN ligand-620

Catalog No.: A80745
Ligand for E3 Ligase
CRBN ligand-620 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be conjugated to a target protein ligand through a linker to create a PROTAC, which enhances targeted protein degradation. CRBN ligand-620 is relevant for research applications in protein modulation and therapeutic development, particularly in the study of protein homeostasis.
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Biological Activity
DescriptionCRBN ligand-620 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be conjugated to a target protein ligand through a linker to create a PROTAC, which enhances targeted protein degradation. CRBN ligand-620 is relevant for research applications in protein modulation and therapeutic development, particularly in the study of protein homeostasis.
Product Information
Catalog NumA80745
FormulaC14H11N3O4
Molecular Weight285.26
CAS Number2925102-22-1
SMILESO=C(O)C=1C=CC(=C2C=NC=CC12)N3C(=O)NC(=O)CC3
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