CRBN ligand-624

Catalog No.: A80815
Ligand for E3 Ligase
CRBN ligand-624 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), designed to facilitate the recruitment of the cereblon protein. This molecule can be conjugated to a target protein ligand through a linker, thereby enabling the formation of a PROTAC (proteolysis-targeting chimera). Its utility in targeted protein degradation makes it a valuable tool in research applications aimed at modulating protein levels within cellular systems.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-624 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), designed to facilitate the recruitment of the cereblon protein. This molecule can be conjugated to a target protein ligand through a linker, thereby enabling the formation of a PROTAC (proteolysis-targeting chimera). Its utility in targeted protein degradation makes it a valuable tool in research applications aimed at modulating protein levels within cellular systems.
Product Information
Catalog NumA80815
FormulaC12H10N4O4
Molecular Weight274.24
CAS Number2925099-90-5
SMILESO=C(O)C=1C=C(C=C2NN=CC21)N3C(=O)NC(=O)CC3
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