Documents & Downloads

CRBN ligand-629

Ligand for E3 Ligase

CRBN ligand-629 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of cereblon to specific target proteins. This compound can be employed in the design of PROTACs (PROteolysis-TArgeting Chimeras) by linking it to a target protein ligand through a suitable linker. Its application in targeted protein degradation makes it a valuable tool for researchers investigating novel therapeutic approaches in cancer and other diseases.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925095-54-9
Applications	Ligand for E3 Ligase
Formula	C₁₄H₁₁N₃O₄
Molecular Weight	285.26
SMILES	O=C(O)C=1C=C2C=CN=CC2=C(C1)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.