CRBN ligand-630

Catalog No.: A80966
Ligand for E3 Ligase
CRBN ligand-630 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be effectively coupled with target protein ligands via a linker to create a proteolysis-targeting chimera (PROTAC). CRBN ligand-630 is valuable in studies of targeted protein degradation and the modulation of cellular processes through ubiquitin-mediated pathways.
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Adooq Products cited in reputable paper
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Biological Activity
DescriptionCRBN ligand-630 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be effectively coupled with target protein ligands via a linker to create a proteolysis-targeting chimera (PROTAC). CRBN ligand-630 is valuable in studies of targeted protein degradation and the modulation of cellular processes through ubiquitin-mediated pathways.
Product Information
Catalog NumA80966
FormulaC14H11N3O4
Molecular Weight285.26
CAS Number2925095-48-1
SMILESO=C(O)C1=NC=CC=2C=CC(=CC21)N3C(=O)NC(=O)CC3
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