Documents & Downloads

CRBN ligand-630

Ligand for E3 Ligase

CRBN ligand-630 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be effectively coupled with target protein ligands via a linker to create a proteolysis-targeting chimera (PROTAC). CRBN ligand-630 is valuable in studies of targeted protein degradation and the modulation of cellular processes through ubiquitin-mediated pathways.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925095-48-1
Applications	Ligand for E3 Ligase
Formula	C₁₄H₁₁N₃O₄
Molecular Weight	285.26
SMILES	O=C(O)C1=NC=CC=2C=CC(=CC21)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.