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CRBN ligand-635

Ligand for E3 Ligase

CRBN ligand-635 is an E3 ubiquitin ligase ligand specifically designed to interact with cereblon (CRBN). This compound facilitates the recruitment of the CRBN protein, enabling targeted protein degradation by forming a PROTAC when conjugated with a target protein ligand through a linker. The biological activity of CRBN ligand-635 makes it valuable for research applications focused on protein homeostasis and novel therapeutic strategies in cellular and molecular biology.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925087-78-9
Applications	Ligand for E3 Ligase
Formula	C₁₂H₁₀N₄O₄
Molecular Weight	274.24
SMILES	O=C(O)C1=NNC2=C1C=CC=C2N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.