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CRBN ligand-656

Ligand for E3 Ligase

CRBN ligand-656 is an E3 ubiquitin ligase ligand that specifically recruits the cereblon (CRBN) protein. It serves as a critical component in the development of PROTACs by linking to target protein ligands through a spacer or linker. This functionality enables selective degradation of target proteins, facilitating research in protein regulation and therapeutic interventions in diverse biological systems.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2902654-77-5
Applications	Ligand for E3 Ligase
Formula	C₁₈H₂₂N₂O₄
Molecular Weight	330.38
SMILES	O=CC1CCN(C2=CC=C(C=C2OC)C3C(=O)NC(=O)CC3)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.