CRBN ligand-658 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN in cellular systems. It is designed for the development of proteolysis-targeting chimeras (PROTACs) by linking to target protein ligands via a suitable linker. This compound is useful in investigating ubiquitin-proteasome pathway mechanisms and advancing targeted protein degradation research.
CRBN ligand-658 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN in cellular systems. It is designed for the development of proteolysis-targeting chimeras (PROTACs) by linking to target protein ligands via a suitable linker. This compound is useful in investigating ubiquitin-proteasome pathway mechanisms and advancing targeted protein degradation research.
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