Documents & Downloads

CRBN ligand-659

Ligand for E3 Ligase

CRBN ligand-659 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to a target protein ligand through a suitable linker, enabling the development of PROTACs (proteolysis-targeting chimeras). Its utility in research lies in targeted protein degradation and the modulation of cellular pathways, making it a valuable tool for studying protein function and therapeutic interventions.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2858743-54-9
Applications	Ligand for E3 Ligase
Formula	C₁₈H₂₂N₂O₄
Molecular Weight	330.38
SMILES	O=CC1CCN(C2=CC=C(C(OC)=C2)C3C(=O)NC(=O)CC3)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.