Documents & Downloads

CRBN ligand-666

Ligand for E3 Ligase

CRBN ligand-666 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound can be utilized in PROTAC (proteolysis-targeting chimeras) approaches, enabling targeted protein degradation for research in cellular processes and therapeutic development. Its applications include studying the ubiquitin-proteasome system and exploring novel pathways for disease intervention.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925090-46-4
Applications	Ligand for E3 Ligase
Formula	C₁₃H₁₅N₃O₂
Molecular Weight	245.28
SMILES	O=C1NC(=O)CCN1C2=CC=CC3=C2CNCC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.