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CRBN ligand-683

Ligand for E3 Ligase

CRBN ligand-683 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound is particularly valuable for the development of PROTAC (Proteolysis Targeting Chimeras) by linking to target protein ligands through a suitable linker. CRBN ligand-683 is instrumental in studies of targeted protein degradation and may be harnessed in various research applications related to proteostasis and disease modulation.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	3031608-64-4
Applications	Ligand for E3 Ligase
Formula	C₂₁H₂₉N₃O₂
Molecular Weight	355.48
SMILES	O=C1NC(=O)C(C2=CC(=CC=C2C)N3CCC4(CCNCC4)CC3)CC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.