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CRBN ligand-687

Ligand for E3 Ligase

CRBN ligand-687 is a small molecule ligand that targets the E3 ubiquitin ligase cereblon (CRBN). It is designed to facilitate the recruitment of cereblon to specific target proteins, enabling the formation of PROTACs (Proteolysis Targeting Chimeras). This compound is valuable for studies related to targeted protein degradation and offers potential applications in therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925097-91-0
Applications	Ligand for E3 Ligase
Formula	C₁₄H₁₃N₃O₃
Molecular Weight	271.28
SMILES	O=CC1=CC=C(C2=C1C=CN2C)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.