Fig. 1 · Structure

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CRBN ligand-688

Ligand for E3 Ligase

CRBN ligand-688 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating its recruitment to target proteins. This compound can be utilized in the design of PROTACs (Proteolysis Targeting Chimeras) by linking it to a target protein ligand via a suitable linker. CRBN ligand-688 is valuable for research applications focused on targeted protein degradation and the exploration of synthetic biology pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 2925097-61-4
Applications Ligand for E3 Ligase
Formula C14H13N3O3
Molecular Weight 271.28
SMILES
O=CC1=CN(C=2C=C(C=CC12)N3C(=O)NC(=O)CC3)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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