CRBN ligand-690 serves as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. Through the conjugation of CRBN ligand-690 with a target protein ligand via a linker, it enables the formation of PROTACs (proteolysis-targeting chimeras). This reagent is instrumental in studies aimed at targeted protein degradation and the modulation of protein abundance in various biological systems.
CRBN ligand-690 serves as a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to target proteins. Through the conjugation of CRBN ligand-690 with a target protein ligand via a linker, it enables the formation of PROTACs (proteolysis-targeting chimeras). This reagent is instrumental in studies aimed at targeted protein degradation and the modulation of protein abundance in various biological systems.
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