CRBN Ligand-694 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound can be conjugated with a target protein ligand through a linker to create a PROTAC (Proteolysis Targeting Chimera), enabling targeted protein degradation. Its applications are valuable in chemical biology and therapeutic research, particularly in the study of protein modulation and the ubiquitin-proteasome system.
CRBN Ligand-694 is a potent ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of CRBN to specific target proteins. This compound can be conjugated with a target protein ligand through a linker to create a PROTAC (Proteolysis Targeting Chimera), enabling targeted protein degradation. Its applications are valuable in chemical biology and therapeutic research, particularly in the study of protein modulation and the ubiquitin-proteasome system.
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