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CRBN ligand-697

Ligand for E3 Ligase

CRBN ligand-697 is an effective ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound is designed to facilitate the recruitment of the cereblon protein, enabling targeted protein degradation through the development of PROTACs (proteolysis-targeting chimeras). Its application in research allows for the modulation of protein levels, providing insights into cellular mechanisms and potential therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925079-50-9
Applications	Ligand for E3 Ligase
Formula	C₁₄H₁₃N₃O₃
Molecular Weight	271.28
SMILES	O=CC1=CC(=CC2=C1C=CN2C)N3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.