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CRBN ligand-701

Ligand for E3 Ligase

CRBN ligand-701 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the CRBN protein. This compound can be conjugated to target protein ligands through a linker to create PROTAC molecules, enabling targeted protein degradation. Its applications extend to research in targeted therapy and the study of protein regulation within cellular systems.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925072-72-4
Applications	Ligand for E3 Ligase
Formula	C₁₄H₁₆N₄O₃
Molecular Weight	288.31
SMILES	O=C1NC(=O)CCN1C=2C=CC=C3C(=O)N(CC32)CCN

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.