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CRBN ligand-703

Ligand for E3 Ligase

CRBN ligand-703 functions as a ligand for the E3 ubiquitin ligase cereblon (CRBN) and is utilized to recruit the CRBN protein effectively. This compound can be conjugated to target protein ligands through a linker, enabling the formation of proteolysis-targeting chimeras (PROTACs). It serves as a valuable tool in chemical biology for the investigation of targeted protein degradation pathways and associated therapeutic applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2925070-80-8
Applications	Ligand for E3 Ligase
Formula	C₁₄H₁₃N₃O₃
Molecular Weight	271.28
SMILES	O=CC1=CC=2C=CN(C2C(=C1)N3C(=O)NC(=O)CC3)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.